Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365513 | 0.86 | TP53 (0.45) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7745460 | 0.78 | TSHR (0.61) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7745467 | 0.78 | TOP2A (0.49) | LMNAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7740405 | 0.78 | KDM4E (0.43) | LMNAMEN1KMT2AKDM4EAKR1B1 | |
| SCHEMBL7745216 | 0.77 | TSHR (0.50) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7745019 | 0.76 | KDM4E (0.47) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7747798 | 0.76 | MEN1 (0.41) | LMNASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7745475 | 0.76 | AKR1B1 (0.41) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7745217 | 0.75 | AGTR1 (0.39) | LMNAALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL7740409 | 0.75 | MEN1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |