Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001907 | 0.78 | KDM4E (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28772866 | 0.78 | KDM4E (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10892274 | 0.77 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28688992 | 0.72 | MEN1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11567274 | 0.72 | CA12 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27593853 | 0.70 | LMNA (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9191388 | 0.69 | CYP3A4 (0.44) | CA12CA1CA2CA9TSHR | |
| SCHEMBL15527861 | 0.68 | MCL1 (0.66) | TSHRDRD4ALDH1A1HSD17B10LMNA | |
| SCHEMBL10893735 | 0.68 | KDM4E (0.49) | KDM4EHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL28758016 | 0.68 | BCL9 (0.48) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002351-A2 | METHOD FOR PREPARING A HYDROXYLATED ARYLHYDRAZINE, INTERMEDIATE PRODUCTS AND METHOD FOR OBTAINING SAME | RHODIA CHIMIE (FR) | 2001-01-11 | — | — | WO | disclosed |