Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285619 | 0.85 | HKDC1 (0.35) | BACE1BTN3A1 | |
| SCHEMBL7285190 | 0.80 | CA2 (0.34) | BACE1CA2CA4CA5AMEN1 | |
| SCHEMBL906701 | 0.80 | CA2 (0.47) | POLBCA1CA2MEN1KMT2A | |
| SCHEMBL20201343 | 0.79 | CYP2C19 (0.37) | POLBBACE1CA12CA1CA2 | |
| SCHEMBL31588025 | 0.79 | POLB (0.63) | POLBBACE1MEN1KMT2AHMGCR | |
| SCHEMBL7745497 | 0.78 | AGXT (0.47) | LTA4HEPHX2POLBCA12CA1 | |
| SCHEMBL15489965 | 0.76 | TDP1 (0.37) | TDP1BACE1KMT2AALDH1A1 | |
| SCHEMBL6829825 | 0.75 | TDP1 (0.49) | LTA4HEPHX2POLBTDP1CCNT1 | |
| SCHEMBL11140840 | 0.73 | POLB (0.54) | LTA4HEPHX2POLBTDP1CA12 | |
| SCHEMBL22021303 | 0.73 | MAPT (0.46) | EPHX2TDP1BTN3A1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |