Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201343 | 0.88 | CYP2C19 (0.37) | CA2CA1BCHEACHEPOLB | |
| SCHEMBL7745488 | 0.80 | LTA4H (0.39) | CA2CA1MEN1POLBGAA | |
| SCHEMBL31588412 | 0.80 | KMT2A (0.33) | CA2CA1BCHEACHEMEN1 | |
| SCHEMBL5026807 | 0.76 | CA2 (0.70) | CA2CA1BCHEACHEMEN1 | |
| SCHEMBL4496052 | 0.74 | PREP (0.48) | CA1MAPT | |
| SCHEMBL22021303 | 0.74 | MAPT (0.46) | GAABTN3A1CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL15489965 | 0.73 | TDP1 (0.37) | KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL906817 | 0.72 | CA2 (0.57) | CA2CA1BCHEACHEMEN1 | |
| SCHEMBL4627288 | 0.72 | CA2 (0.57) | CA2CA1BCHEACHEMEN1 | |
| SCHEMBL906952 | 0.72 | CA2 (0.57) | CA2CA1BCHEACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745365-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| EP-3312292-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2019-09-25 | — | — | EP | disclosed |
| EP-1885875-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2019-05-22 | — | — | EP | disclosed |
| US-20190031629-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2019-01-31 | — | — | US | disclosed |
| US-10077244-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2018-09-18 | — | — | US | disclosed |
| EP-3312292-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | Promega Corporation (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-2778234-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2017-09-27 | — | — | EP | disclosed |
| US-20160176830-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-06-23 | — | — | US | disclosed |
| US-20160176830-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-06-23 | — | — | US | disclosed |
| US-20160176830-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-06-23 | — | — | US | disclosed |
| US-7951550-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2011-05-31 | — | — | US | disclosed |
| EP-2277872-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2272973-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-12 | — | — | EP | disclosed |
| EP-2272972-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-12 | — | — | EP | disclosed |
| US-20080299593-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2008-12-04 | — | — | US | disclosed |
| US-20080299593-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2008-12-04 | — | — | US | disclosed |
| EP-1935986-A2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1885875-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2007-01-18 | — | — | US | disclosed |
| WO-2006130551-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745365-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | CA2 1062/4885CA1 1484/4885BCHE 2660/4885 |
| US-10077244-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | CA2 1023/4885CA1 1370/4885BCHE 2605/4885 |
| US-20080299593-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | CA2 1062/4885CA1 1484/4885BCHE 2660/4885 |
| US-20190031629-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | GLB1, NOD1, PYCARD | CA2 1062/4885CA1 1484/4885BCHE 2660/4885 |
| US-20160176830-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | GLB1, NOD1, PYCARD | CA2 1023/4885CA1 1370/4885BCHE 2605/4885 |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | CA2 1981/4885CA1 2019/4885BCHE 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.