Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906701 | 0.88 | CA2 (0.47) | CYP2C19SMN1; SMN2POLBBTN3A1CA1 | |
| SCHEMBL7745488 | 0.79 | LTA4H (0.39) | POLBBTN3A1CA1CA2ALDH1A1 | |
| SCHEMBL20201349 | 0.76 | SMN1; SMN2 (0.61) | CYP2C19SMN1; SMN2POLBCA1CA2 | |
| SCHEMBL20201336 | 0.73 | CYP2C19 (0.45) | CYP2C19SMN1; SMN2POLBCA1CA2 | |
| SCHEMBL19420438 | 0.73 | CYP2C19 (0.49) | CYP2C19SMN1; SMN2POLBCA1CA2 | |
| SCHEMBL4496052 | 0.73 | PREP (0.48) | CA1PREPBACE1CA12CA9 | |
| SCHEMBL15489965 | 0.72 | TDP1 (0.37) | NPC1RAB9AALDH1A1BACE1 | |
| SCHEMBL19420441 | 0.72 | ALDH1A1 (0.46) | CYP2C19SMN1; SMN2POLBCA1CA2 | |
| SCHEMBL9665663 | 0.71 | PPARA (0.37) | BTN3A1ALDH1A1 | |
| SCHEMBL31588412 | 0.71 | KMT2A (0.33) | SMN1; SMN2POLBCA1CA2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180149596-A1 | NEAR-INFRARED FLUORESCENT PROBE FOR DETECTING ALKALINE PHOSPHATASE AND MANUFACTURING METHOD THEREOF | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180149596-A1 | NEAR-INFRARED FLUORESCENT PROBE FOR DETECTING ALKALINE PHOSPHATASE AND MANUFACTURING METHOD THEREOF | ALPL, ALPI, ALPP | CYP2C19 3206/4885SMN1; SMN2 4224/4885POLB 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.