Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746888 | 0.89 | TDP1 (0.45) | TDP1CHRM1CNR1CNR2ALDH1A1 | |
| SCHEMBL7745653 | 0.89 | TDP1 (0.45) | TDP1CHRM1ALDH1A1PCSK9PKM | |
| SCHEMBL7741914 | 0.75 | ALDH1A1 (0.54) | CNR2ALDH1A1RECQLHTTL3MBTL1 | |
| SCHEMBL7746367 | 0.74 | ALDH1A1 (0.48) | CNR2ALDH1A1RECQLHTTL3MBTL1 | |
| SCHEMBL7115198 | 0.72 | TDP1 (0.55) | TDP1CHRM1PKMHTTKMT2A | |
| SCHEMBL7746533 | 0.72 | TDP1 (0.56) | TDP1CHRM1ALDH1A1PKMHTT | |
| SCHEMBL3238752 | 0.71 | TDP1 (0.50) | TDP1CHRM1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3238812 | 0.71 | CHRM1 (0.57) | TDP1CHRM1SMN1; SMN2LMNAPOLB | |
| SCHEMBL1481951 | 0.70 | LMNA (0.48) | TDP1CHRM1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7746499 | 0.69 | MEN1 (0.42) | RECQLL3MBTL1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |