Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746367 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HTTLMNAKDM4EL3MBTL1 | |
| SCHEMBL7746351 | 0.87 | FEN1 (0.44) | ALDH1A1HTTLMNAKDM4ERECQL | |
| SCHEMBL7747488 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1HTTLMNAL3MBTL1RECQL | |
| SCHEMBL14848270 | 0.76 | KDM4E (0.66) | ALDH1A1HTTLMNAKDM4EL3MBTL1 | |
| SCHEMBL7745656 | 0.75 | TDP1 (0.45) | ALDH1A1HTTLMNAKDM4EL3MBTL1 | |
| SCHEMBL7746911 | 0.74 | MEN1 (0.45) | ALDH1A1LMNAKDM4EL3MBTL1RECQL | |
| SCHEMBL7745691 | 0.73 | SMN1; SMN2 (0.47) | ALDH1A1LMNAKDM4EL3MBTL1RECQL | |
| SCHEMBL7746317 | 0.72 | MEN1 (0.43) | ALDH1A1HTTLMNAL3MBTL1RECQL | |
| SCHEMBL14829909 | 0.72 | ALDH1A1 (0.80) | ALDH1A1HTTLMNAKDM4EL3MBTL1 | |
| SCHEMBL7746499 | 0.72 | MEN1 (0.42) | L3MBTL1RECQLSMN1; SMN2USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |