Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741587 | 0.90 | MAPT (0.69) | MAPTLMNAKMT2AALDH1A1NPSR1 | |
| SCHEMBL117687 | 0.85 | GAA (0.56) | MAPTLMNAKMT2AALDH1A1GAA | |
| SCHEMBL27847152 | 0.83 | MAPT (0.58) | MAPTLMNAKMT2AALDH1A1GAA | |
| SCHEMBL7745736 | 0.82 | ALDH1A1 (0.59) | MAPTLMNAKMT2AALDH1A1NPSR1 | |
| SCHEMBL27653716 | 0.82 | GAA (0.53) | MAPTLMNAKMT2AALDH1A1GAA | |
| SCHEMBL116789 | 0.82 | MAPT (0.53) | MAPTLMNAKMT2AALDH1A1GAA | |
| SCHEMBL22478744 | 0.82 | ALDH1A1 (0.50) | MAPTLMNAKMT2AALDH1A1NPSR1 | |
| SCHEMBL8985656 | 0.81 | KAT2B (0.64) | MAPTKMT2AALDH1A1NPSR1GAA | |
| SCHEMBL29064843 | 0.80 | ALDH1A1 (0.57) | MAPTLMNAKMT2AALDH1A1GAA | |
| SCHEMBL5352344 | 0.80 | ALDH1A1 (0.80) | MAPTLMNAKMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |