Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HEXA | P06865 | 1/20 | 0.39 |
| ▸ | HEXB | P07686 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745816 | 0.88 | HEXA (0.53) | POLBHEXAHEXBTOP2ATSHR | |
| SCHEMBL11373888 | 0.78 | HEXA (0.57) | POLBHEXAHEXBKDM4EALDH1A1 | |
| SCHEMBL7745712 | 0.78 | PKM (0.48) | POLBHEXAHEXBTOP2ATSHR | |
| SCHEMBL7745462 | 0.78 | POLB (0.46) | POLBTOP2AALDH1A1LMNAMAPT | |
| SCHEMBL7745469 | 0.75 | HPGD (0.46) | POLBTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL11369587 | 0.73 | POLB (0.59) | POLBHEXAHEXBTSHRKDM4E | |
| SCHEMBL7745817 | 0.73 | HPGD (0.49) | POLBTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL7746704 | 0.72 | TOP2A (0.55) | POLBTOP2ATSHRKDM4EALDH1A1 | |
| SCHEMBL7740999 | 0.72 | HTR2A (0.61) | POLBTOP2ATSHRKDM4EALDH1A1 | |
| SCHEMBL7744925 | 0.71 | POLB (0.47) | POLBTOP2ATSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |