Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745469 | 0.91 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2CASP1MPI | |
| SCHEMBL7745712 | 0.83 | PKM (0.48) | HPGDALDH1A1SMN1; SMN2CASP1MPI | |
| SCHEMBL7745816 | 0.83 | HEXA (0.53) | HPGDALDH1A1SMN1; SMN2CASP1MPI | |
| SCHEMBL7745820 | 0.73 | POLB (0.41) | HPGDALDH1A1L3MBTL1LMNATSHR | |
| SCHEMBL7740562 | 0.69 | TSHR (0.57) | ALDH1A1SMN1; SMN2LMNATSHRPOLB | |
| SCHEMBL7745462 | 0.69 | POLB (0.46) | ALDH1A1LMNAPOLB | |
| SCHEMBL29437299 | 0.69 | ALDH1A1 (1.00) | HPGDALDH1A1SMN1; SMN2CASP1MPI | |
| SCHEMBL6270684 | 0.69 | ALDH1A1 (1.00) | HPGDALDH1A1SMN1; SMN2CASP1MPI | |
| SCHEMBL7745697 | 0.69 | TSHR (0.64) | HPGDALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL7740965 | 0.67 | TSHR (0.49) | ALDH1A1SMN1; SMN2L3MBTL1TSHRPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |