Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703078 | 0.81 | POLB (0.48) | MAPTGAAKDM4EALOX12HTT | |
| SCHEMBL9558860 | 0.79 | MAPT (0.49) | MAPTGAAKDM4EALOX12HTT | |
| SCHEMBL9558402 | 0.76 | MAPT (0.50) | MAPTGAAKDM4EALOX12HTT | |
| SCHEMBL7701328 | 0.70 | TDP1 (0.48) | MAPTGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7698688 | 0.69 | HDAC3 (0.51) | MAPTGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7698636 | 0.68 | HPGD (0.48) | MAPTGAAKDM4EHTTKMT2A | |
| SCHEMBL10567638 | 0.68 | POLB (0.60) | MAPTGAAKDM4EALOX12HTT | |
| SCHEMBL30229280 | 0.68 | HDAC3 (0.52) | MAPTGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL9475290 | 0.67 | LMNA (0.63) | KDM4EHTTSMN1; SMN2KMT2APOLB | |
| SCHEMBL9559110 | 0.67 | TDP1 (0.50) | MAPTGAAKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021166-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-03-29 | — | — | WO | claimed |