Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559096 | 0.87 | LMNA (0.51) | MAPTHTTKMT2ATDP1GAA | |
| SCHEMBL9559123 | 0.86 | L3MBTL1 (0.49) | MAPTHTTL3MBTL1KMT2ATDP1 | |
| SCHEMBL9558860 | 0.81 | MAPT (0.49) | MAPTHTTL3MBTL1KMT2ARXFP1 | |
| SCHEMBL7703078 | 0.79 | POLB (0.48) | MAPTHTTL3MBTL1KMT2ARXFP1 | |
| SCHEMBL7745895 | 0.76 | MAPT (0.45) | MAPTHTTL3MBTL1KMT2ARXFP1 | |
| SCHEMBL9558798 | 0.75 | KMT2A (0.60) | MAPTHTTKMT2ARXFP1GAA | |
| SCHEMBL9838242 | 0.75 | TDP1 (0.44) | MAPTL3MBTL1KMT2ATDP1KDM4E | |
| SCHEMBL9558821 | 0.75 | LMNA (0.45) | MAPTHTTL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL9551140 | 0.74 | AKR1C3 (0.45) | MAPTHTTL3MBTL1KMT2AKDM4E | |
| SCHEMBL10516959 | 0.74 | AKR1C3 (0.45) | MAPTHTTL3MBTL1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225444-A | Antiinflammatory agents or antiallergens | G. D. SEARLE & CO. (US) | 1993-07-06 | — | — | US | disclosed |
| US-5071876-A | Antiinflammatory agent; antiallergen; skin disorders; asthma; enzyme inhibitors of 5-lipogenase | G. D. SEARLE & CO. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0190682-A2 | Novel disubstituted 4-hydroxyphenylthio anilides | G.D. Searle & Co. (US) | 1986-08-13 | — | — | EP | disclosed |