Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | GNRHR | P30968 | 8/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745715 | 0.90 | AGTR1 (0.35) | TBXA2RPLK1GNRHR | |
| SCHEMBL7745380 | 0.86 | TBXA2R (0.39) | TBXA2RPTGS2CA12CA1CA2 | |
| SCHEMBL7746063 | 0.83 | IDO1 (0.35) | TBXA2RPTGS2CA12CA1CA2 | |
| SCHEMBL7741233 | 0.83 | TBXA2R (0.34) | TBXA2RPTGS2CA12CA1CA2 | |
| SCHEMBL7741627 | 0.78 | CNR2 (0.38) | TBXA2R | |
| SCHEMBL7745974 | 0.75 | DRD2 (0.42) | TBXA2R | |
| SCHEMBL7741465 | 0.75 | AGTR1 (0.36) | TBXA2R | |
| SCHEMBL7741469 | 0.73 | PTGDR2 (0.42) | TBXA2RCA12CA1CA2CA9 | |
| SCHEMBL7746035 | 0.73 | AGTR1 (0.36) | TBXA2R | |
| SCHEMBL7745634 | 0.73 | ALDH1A1 (0.37) | TBXA2RCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |