Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809805 | 0.81 | GAA (0.41) | GRK5TYRO3DYRK1BGAAMAPT | |
| SCHEMBL7746356 | 0.72 | GAA (0.43) | GRK5TYRO3DYRK1BGAAMAPT | |
| Benzene SCHEMBL27623238 | 0.63 | KDM4E (0.59) | GRK5TYRO3DYRK1BGAAMAPT | |
| SCHEMBL62942 | 0.63 | KDM4E (0.59) | GRK5TYRO3DYRK1BGAAMAPT | |
| SCHEMBL123633 | 0.60 | GRK5 (0.56) | GRK5TYRO3DYRK1BGAAMAPT | |
| SCHEMBL6275433 | 0.60 | GRK5 (0.52) | GRK5TYRO3DYRK1BGAAMAPT | |
| SCHEMBL6032227 | 0.59 | GAA (0.63) | GRK5TYRO3DYRK1BGAAMAPT | |
| SCHEMBL5964903 | 0.58 | MGLL (0.37) | GAAALDH1A1GSK3AGSK3BPTPN1 | |
| SCHEMBL8024211 | 0.58 | GAA (0.42) | GRK5TYRO3DYRK1BGAAALDH1A1 | |
| SCHEMBL27345565 | 0.58 | MGLL (0.52) | GAAALDH1A1GSK3AGSK3BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |