Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | G6PD | P11413 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745982 | 0.72 | GRK5 (0.47) | GAAKDM4EMAPTTDP1GRK5 | |
| SCHEMBL7741931 | 0.71 | MEN1 (0.55) | GAATDP1MEN1KMT2ADDB1 | |
| SCHEMBL62942 | 0.70 | KDM4E (0.59) | GAAKDM4EMAPTTDP1GRK5 | |
| Benzene SCHEMBL27623238 | 0.70 | KDM4E (0.59) | GAAKDM4EMAPTTDP1GRK5 | |
| SCHEMBL123633 | 0.68 | GRK5 (0.56) | GAAKDM4EMAPTTDP1GRK5 | |
| SCHEMBL14916963 | 0.66 | ALOX5 (0.46) | GAAKDM4EMAPTTDP1ALOX5 | |
| SCHEMBL4284163 | 0.62 | ALOX5 (0.50) | GAAKDM4EMAPTTDP1ALOX5 | |
| SCHEMBL3809805 | 0.60 | GAA (0.41) | GAAKDM4EMAPTTDP1GRK5 | |
| SCHEMBL9751665 | 0.60 | MEN1 (0.40) | GAAKDM4EMAPTTDP1GRK5 | |
| SCHEMBL10649531 | 0.60 | EPHX2 (0.62) | GAAMEN1KMT2ADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |