Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752783 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP3A4PTPN1L3MBTL1LMNA | |
| SCHEMBL999002 | 0.83 | CA2 (0.59) | ALDH1A1LMNAMAPTCA1CA2 | |
| SCHEMBL7769730 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CTSBL3MBTL1CA1 | |
| SCHEMBL5840961 | 0.82 | CA1 (0.64) | ALDH1A1CYP3A4CTSBL3MBTL1MAPT | |
| SCHEMBL9186437 | 0.81 | PTPN1 (0.56) | ALDH1A1PTPN1L3MBTL1LMNAMAPT | |
| SCHEMBL31646963 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CTSBL3MBTL1CA1 | |
| SCHEMBL5840098 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CTSBL3MBTL1CA1 | |
| SCHEMBL7750641 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL5786092 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP3A4PTPN1L3MBTL1LMNA | |
| SCHEMBL31646617 | 0.76 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CTSBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597304-B1 | Use of substituted benzimidazoles for combating parasitic protozoas | BAYER AG (DE) | 2001-01-10 | — | — | EP | disclosed |
| US-5877195-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5863933-A | NEMATOCIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-26 | — | — | US | disclosed |
| EP-0596358-B1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5656649-A | PESTICIDE, INSECTICIDES, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |
| US-5585395-A | INSECTICIDES, MITICIDES, FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5484953-A | CHEMICAL INTERMEDIATES FOR BENZIMIDAZOLES FOR INSECTICIDES OR NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-16 | — | — | US | disclosed |
| US-5482956-A | ANTIPROTOZOA AGENTS FOR ANIMALS OR INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
| EP-0597304-A1 | Use of substituted benzimidazoles | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| EP-0596358-A1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1994-05-11 | — | — | EP | disclosed |