SCHEMBL7769730

SCHEMBL7769730

Nc1c(Br)cc(S(=O)(=O)F)cc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
CYP3A4 P08684 1/20 0.56
CTSB P07858 1/20 0.50
CA9 Q16790 11/20 0.46
CA1 P00915 10/20 0.46
CA2 P00918 10/20 0.46
CA12 O43570 6/20 0.46
CA3 P07451 1/20 0.46
VCAM1 P19320 2/20 0.44
NSD2 O96028 1/20 0.42
GAA P10253 1/20 0.42
PLCG1 P19174 1/20 0.42
DNMT1 P26358 1/20 0.42
CASP6 P55212 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 1/20 0.41
CA4 P22748 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5840961 0.86 CA1 (0.64) ALDH1A1CYP3A4CTSBCA9CA1
SCHEMBL5840098 0.83 ALDH1A1 (0.56) ALDH1A1CYP3A4CTSBCA9CA1
SCHEMBL31646963 0.83 ALDH1A1 (0.56) ALDH1A1CYP3A4CTSBCA9CA1
SCHEMBL7745986 0.82 ALDH1A1 (0.51) ALDH1A1CYP3A4CTSBCA9CA1
SCHEMBL7769087 0.81 VCAM1 (0.50) ALDH1A1CYP3A4CA9CA1CA2
SCHEMBL7772190 0.81 CA2 (0.67) CA9CA1CA2CA12CA3
SCHEMBL31646617 0.76 ALDH1A1 (0.49) ALDH1A1CYP3A4CTSBCA9CA1
SCHEMBL11608006 0.76 CA2 (0.69) ALDH1A1CYP3A4CTSBCA9CA1
SCHEMBL31647148 0.75 ALDH1A1 (0.47) ALDH1A1CYP3A4CTSBCA9CA1
SCHEMBL31646933 0.75 ALDH1A1 (0.47) ALDH1A1CYP3A4CTSBCA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1089099-C Monoazo dyes substituted by haloalkylacarbamate and sulphonylfluoride group BASF AG (DE) 2002-08-14 CN disclosed
EP-0740690-B1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF SYNGENTA LTD (GB) 2001-06-20 EP disclosed
EP-0923621-B1 MONOAZO DYES SUBSTITUTED BY HALOALKYLCARBAMATE AND SULPHONYLFLUORIDE GROUPS DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-05-16 EP disclosed
US-5973127-A WATER INSOLUBILITY; COLORING SYNTHETIC TEXTILE FABRICS BASF AKTIENGESELLSCHAFT (DE) 1999-10-26 US disclosed
CN-1225656-A Monoazo dyes substituted by haloalkyl carbamate and sulfonyl fluoride BASF AG (DE) 1999-08-11 CN disclosed
EP-0923621-A1 MONOAZO DYES SUBSTITUTED BY HALOALKYLCARBAMATE AND SULPHONYLFLUORIDE GROUPS BASF AKTIENGESELLSCHAFT (DE) 1999-06-23 EP disclosed
WO-1997049770-A9 MONOAZO DYES SUBSTITUTED BY HALOALKYLCARBAMATE AND SULPHONYLFLUORIDE GROUPS 1998-12-23 WO disclosed
US-5739299-A GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES ZENECA LIMITED (GB) 1998-04-14 US disclosed
WO-1997049770-A1 MONOAZO DYES SUBSTITUTED BY HALOALKYLCARBAMATE AND SULPHONYLFLUORIDE GROUPS BASF AKTIENGESELLSCHAFT (DE) 1997-12-31 WO disclosed
EP-0740690-A1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1996-11-06 EP disclosed
WO-1995020014-A1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1995-07-27 WO disclosed