Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745992 | 0.89 | POLB (0.49) | ALDH1A1POLBL3MBTL1LMNAMAPT | |
| SCHEMBL9353785 | 0.81 | NR4A2 (0.68) | NR4A2ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7747969 | 0.81 | TOP2A (0.46) | ALDH1A1POLBL3MBTL1LMNAMAPT | |
| SCHEMBL9353793 | 0.78 | NR4A2 (0.67) | NR4A2ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7745653 | 0.75 | TDP1 (0.45) | ALDH1A1POLBTSHRLMNASMN1; SMN2 | |
| SCHEMBL7746704 | 0.75 | TOP2A (0.55) | ALDH1A1GAAPOLBL3MBTL1TSHR | |
| SCHEMBL7741397 | 0.74 | HDAC1 (0.56) | ALDH1A1POLBMAPTHDAC1HDAC6 | |
| SCHEMBL9540638 | 0.74 | NR4A2 (0.72) | NR4A2ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL5449197 | 0.74 | NR4A2 (0.57) | NR4A2ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7745595 | 0.72 | LMNA (0.65) | ALDH1A1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |