Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA8 | P11142 | 3/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976100 | 0.85 | HSPA8 (0.46) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| SCHEMBL177666 | 0.84 | HSPA8 (0.44) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| SCHEMBL7617960 | 0.84 | ADORA3 (0.43) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| SCHEMBL2197504 | 0.77 | CDK1 (0.48) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| SCHEMBL1665379 | 0.77 | HSPA5 (0.51) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| Ammonia Solution, Strong SCHEMBL28147967 | 0.76 | HSPA5 (0.50) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| SCHEMBL1936249 | 0.76 | ADK (0.50) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| SCHEMBL830796 | 0.76 | MAPK1 (0.50) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| SCHEMBL3841527 | 0.76 | DOT1L (0.50) | HSPA8HSPA5HIF1AADORA3ADORA2A | |
| SCHEMBL724943 | 0.76 | MAPK1 (0.50) | HSPA8HSPA5HIF1AADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708781-B1 | A 3 ADENOSINE RECEPTOR AGONISTS | USA (US) | 2001-10-04 | — | — | EP | disclosed |
| US-5773423-A | XANTHINE RIBOSIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1995002604-A1 | A3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-01-26 | — | — | WO | disclosed |