Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740984 | 0.91 | TBXA2R (0.38) | DRD2TBXA2RTSHRALDH1A1MAPT | |
| SCHEMBL7740752 | 0.89 | DRD2 (0.44) | DRD2TBXA2RTSHRALDH1A1MAPT | |
| SCHEMBL7745904 | 0.89 | DRD2 (0.44) | DRD2TBXA2RALDH1A1MAPTLMNA | |
| SCHEMBL7745936 | 0.88 | TSHR (0.41) | TSHRALDH1A1MAPTLMNAPOLB | |
| SCHEMBL7745974 | 0.87 | DRD2 (0.42) | DRD2TBXA2RALDH1A1MAPTLMNA | |
| SCHEMBL7745710 | 0.85 | AGTR1 (0.38) | DRD2TBXA2RPOLB | |
| SCHEMBL7746299 | 0.84 | TSHR (0.40) | TSHRALDH1A1NPSR1MAPTLMNA | |
| SCHEMBL7746271 | 0.82 | TSHR (0.45) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL7745478 | 0.82 | GRM2 (0.41) | TSHRALDH1A1USP2NPSR1MAPT | |
| SCHEMBL7745883 | 0.81 | AGTR1 (0.42) | ALDH1A1MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |