⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145910 | 0.97 | — | — | |
| SCHEMBL1145973 | 0.97 | CXCR3 (0.46) | — | |
| SCHEMBL774353 | 0.92 | — | — | |
| SCHEMBL49179 | 0.79 | — | — | |
| SCHEMBL5320056 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL1144548 | 0.77 | — | — | |
| SCHEMBL8185904 | 0.77 | CXCR3 (0.42) | — | |
| SCHEMBL8185902 | 0.77 | CXCR3 (0.42) | — | |
| SCHEMBL954500 | 0.77 | CXCR3 (0.42) | — | |
| SCHEMBL199976 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296700-B2 | Method for purifying a pyrazolinone derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-29 | — | — | US | disclosed |
| EP-2441756-B1 | METHOD FOR PURIFYING A PYRAZOLINONE DERIVATIVE | SUMITOMO CHEMICAL CO (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2441756-A1 | METHOD FOR PURIFYING A PYRAZOLINONE DERIVATIVE | Sumitomo Chemical Company, Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-20120071666-A1 | Method for Purifying a Pyrazolinone Derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20110143939-A1 | QUINOXALIN-2-ONE DERIVATIVES, COMPOSITIONS WHICH PROTECT USEFUL PLANTS AND COMPRISE THESE DERIVATIVES, AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2011-06-16 | — | — | US | disclosed |
| US-7888374-B2 | Inhibitors of c-jun N-terminal kinases | ABBOTT LABORATORIES (US) | 2011-02-15 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1072598-B9 | PYRAZOLINONE DERIVATIVES | SUMITOMO CHEMICAL CO (JP) | 2007-01-24 | — | — | EP | disclosed |
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | ABBVIE INC. | 2006-08-03 | — | — | US | disclosed |
| US-20060173022-A1 | Heterocyclic amides, method for the production thereof, substances containing said heterocyclic amides, and use thereof as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2006-08-03 | — | — | US | disclosed |
| EP-1072598-B1 | PYRAZOLINONE DERIVATIVES | SUMITOMO CHEMICAL CO (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | BAYER CROPSCIENCE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
| US-20050171132-A1 | Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists | XIN ZHILI (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |
| US-20040006047-A1 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED | 2004-01-08 | — | — | US | disclosed |
| US-6294567-B1 | CONTROLLING PLANT DISEASES AND GERMACIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1072598-A1 | PYRAZOLINONE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-31 | — | — | EP | disclosed |