SCHEMBL7747037

SCHEMBL7747037

NCCCC1CC[Si](c2ccccc2)(c2ccccc2)OC1(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.35
GRIN2D O15399 2/20 0.35
GRIN3B O60391 2/20 0.35
GRIA1 P42261 2/20 0.35
GRIA2 P42262 2/20 0.35
GRIA3 P42263 2/20 0.35
GRIA4 P48058 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
GRIN2B Q13224 2/20 0.35
GRIN2C Q14957 2/20 0.35
GRIN3A Q8TCU5 2/20 0.35
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
HTR2A P28223 3/20 0.31
HTR2C P28335 2/20 0.31
HTR2B P41595 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28115541 0.73 KDM1A (0.39) MAOBCHRM2CHRM4CHRM1CHRM3
SCHEMBL28228829 0.70 GRIN2D (0.32) MAOBGRIN2DGRIN3BGRIA1GRIA2
SCHEMBL28946258 0.67 GRIN2D (0.38) MAOBGRIN2DGRIN3BGRIA1GRIA2
SCHEMBL28272997 0.62 KDM1A (0.39) MAOBCHRM1
SCHEMBL27503892 0.60 SLC6A2 (0.34) HTR2AHRH1
SCHEMBL28172743 0.59 SLC6A2 (0.33) HTR2AHRH1
SCHEMBL7216822 0.58 OPRM1 (0.39) MAOBGRIN2DGRIN3BGRIA1GRIA2
SCHEMBL2352430 0.58 AKR1C1 (0.35)
SCHEMBL25347295 0.57 MAOA (0.36) MAOB
SCHEMBL2048192 0.57 OPRM1 (0.36) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1064319-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2001-01-03 EP disclosed
WO-1999033902-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed
EP-0892824-A1 COMPOSITION FOR LIQUID CRYSTAL ALIGNING FILM, LIQUID CRYSTAL ALIGNING FILM, LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-01-27 EP disclosed
WO-1998031725-A1 COMPOSITION FOR LIQUID CRYSTAL ALIGNING FILM, LIQUID CRYSTAL ALIGNING FILM, LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1998-07-23 WO disclosed