Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 4/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514581 | 0.86 | HSD11B1 (0.36) | ADORA2AMAPK14ADORA1POLBADORA2B | |
| SCHEMBL8441483 | 0.77 | CYP11B1 (0.35) | — | |
| SCHEMBL7746895 | 0.75 | PTGS2 (0.39) | SLC34A1GRM5MAPK14 | |
| SCHEMBL3488435 | 0.72 | PGR (0.45) | SLC34A1GRM5ADORA2APIK3R1PIK3CA | |
| SCHEMBL8626557 | 0.71 | HSD11B1 (0.38) | SLC34A1ADORA2AMAPK14ADORA1POLB | |
| SCHEMBL8031860 | 0.70 | HSD11B1 (0.40) | SLC34A1GRM5ADORA2AMAPK14ADORA1 | |
| SCHEMBL15332993 | 0.70 | MAPK14 (0.38) | SLC34A1GRM5MAPK14PIK3R1PIK3CA | |
| SCHEMBL31665009 | 0.70 | HTR2A (0.41) | SLC34A1ADORA2AMAPK14PIK3R1PIK3CA | |
| SCHEMBL13184428 | 0.69 | SLC34A1 (0.53) | SLC34A1GRM5ADORA2APOLBADORA2B | |
| SCHEMBL20074778 | 0.69 | SLC34A1 (0.41) | SLC34A1GRM5ADORA2AMAPK14PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001019820-A1 | SUBSTITUTED PYRAZOL-3-YLBENZOXAZINONES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |