SCHEMBL7746895 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PTGS2	P35354	6/20	0.39

▸	PTGS1	P23219	3/20	0.39

▸	MAPK14	Q16539	5/20	0.36

▸	KIT	P10721	1/20	0.36

▸	SLC34A1	Q06495	2/20	0.35

▸	GRM5	P41594	1/20	0.35

▸	BRD4	O60885	1/20	0.34

▸	PDE4B	Q07343	1/20	0.34

▸	PDE4D	Q08499	1/20	0.34

▸	RORC	P51449	1/20	0.33

▸	GAA	P10253	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7513789	0.87	PTGS2 (0.36)	PTGS2PTGS1KITRORC
SCHEMBL8604204	0.77	EGLN2 (0.33)	PDE4BPDE4D
SCHEMBL7506362	0.77	PTGS2 (0.30)	PTGS2
SCHEMBL7741912	0.76	VCAM1 (0.34)	PTGS2GAA
SCHEMBL7747366	0.75	SLC34A1 (0.36)	MAPK14SLC34A1GRM5
SCHEMBL15332993	0.74	MAPK14 (0.38)	MAPK14SLC34A1GRM5BRD4GAA
SCHEMBL7509183	0.73	VCAM1 (0.33)	PTGS2
SCHEMBL9531790	0.73	PTGS2 (0.37)	PTGS2PTGS1KITSLC34A1
SCHEMBL9531665	0.73	KIF11 (0.39)	PTGS2PTGS1KITSLC34A1
SCHEMBL9696394	0.72	RORC (0.31)	RORCGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2001019820-A1	SUBSTITUTED PYRAZOL-3-YLBENZOXAZINONES	BASF AKTIENGESELLSCHAFT (DE)	2001-03-22	—	—	WO	disclosed