Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27441072 | 0.85 | ALDH1A1 (0.51) | ALDH1A1LMNAGLANPC1RAB9A | |
| SCHEMBL7747823 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAGLANPC1RAB9A | |
| SCHEMBL7747380 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAGLANPC1RAB9A | |
| SCHEMBL8794289 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNAGLANPC1RAB9A | |
| SCHEMBL6929828 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNAGLANPC1RAB9A | |
| SCHEMBL8024394 | 0.75 | SLC7A5 (0.54) | ALDH1A1LMNAGLANPC1RAB9A | |
| SCHEMBL27367998 | 0.73 | ALDH1A1 (0.54) | ALDH1A1LMNANPC1RAB9AKMT2A | |
| SCHEMBL3175993 | 0.72 | TSHR (0.49) | NPC1RAB9AKMT2AMEN1CYP3A4 | |
| SCHEMBL27411500 | 0.72 | KMT2A (0.61) | ALDH1A1LMNANPC1RAB9AKMT2A | |
| SCHEMBL8728691 | 0.71 | MDM2 (0.66) | ALDH1A1LMNANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1116718-A2 | Method for the preparation of taxol and its derivatives | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-07-18 | — | — | EP | disclosed |