Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747876 | 1.00 | MGLL (0.39) | MGLLKDM1AGAAMEN1KMT2A | |
| SCHEMBL7995847 | 1.00 | MGLL (0.39) | MGLLKDM1AGAAMEN1KMT2A | |
| SCHEMBL8174001 | 0.87 | ADRA1A (0.42) | MGLLKDM1AGAA | |
| SCHEMBL5658840 | 0.87 | ADRA1A (0.42) | MGLLKDM1AGAA | |
| SCHEMBL5662288 | 0.87 | ADRA1A (0.42) | MGLLKDM1AGAA | |
| SCHEMBL7972575 | 0.84 | MGLL (0.39) | MGLLKDM1AGAA | |
| SCHEMBL8173301 | 0.82 | MGLL (0.43) | MGLL | |
| SCHEMBL7966161 | 0.82 | MGLL (0.43) | MGLL | |
| SCHEMBL7225595 | 0.79 | MGLL (0.41) | MGLLKDM1A | |
| SCHEMBL6222781 | 0.78 | MGLL (0.38) | MGLLKDM1AGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022919-A2 | SPIRO[BICYCLIC -AZACYCLOALKYL AND -CYCLOALKYL] DERIVATIVES AND USES THEREOF | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |