Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.43 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173301 | 1.00 | MGLL (0.43) | MGLLFAAHCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL8174001 | 0.85 | ADRA1A (0.42) | MGLLFAAHCYP1A2CYP2D6 | |
| SCHEMBL5662288 | 0.85 | ADRA1A (0.42) | MGLLFAAHCYP1A2CYP2D6 | |
| SCHEMBL5658840 | 0.85 | ADRA1A (0.42) | MGLLFAAHCYP1A2CYP2D6 | |
| SCHEMBL7995847 | 0.82 | MGLL (0.39) | MGLL | |
| SCHEMBL7747880 | 0.82 | MGLL (0.39) | MGLL | |
| SCHEMBL7747876 | 0.82 | MGLL (0.39) | MGLL | |
| SCHEMBL7972575 | 0.81 | MGLL (0.39) | MGLLFAAHCYP1A2CYP2D6 | |
| SCHEMBL5661991 | 0.79 | MGLL (0.42) | MGLLFAAHCYP1A2CYP2D6 | |
| SCHEMBL5663686 | 0.79 | MGLL (0.42) | MGLLFAAHCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255315-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | disclosed |