Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692713 | 0.79 | — | — | |
| SCHEMBL9412745 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL384789 | 0.76 | AGXT (0.43) | TDP1TP53MAPTHRH3 | |
| SCHEMBL963476 | 0.74 | CA1 (0.34) | — | |
| SCHEMBL483523 | 0.74 | TDP1 (0.44) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL6890461 | 0.74 | ESR1 (0.44) | ALDH1A1CYP3A4HSD17B10CALM1KDM4E | |
| SCHEMBL17937673 | 0.74 | IDO1 (0.41) | ALDH1A1APPKDM4ENPC1GAA | |
| SCHEMBL17937819 | 0.74 | IDO1 (0.41) | ALDH1A1APP | |
| SCHEMBL27999991 | 0.74 | IDO1 (0.52) | ALDH1A1TSHRCYP3A4ALOX15CALM1 | |
| SCHEMBL49102 | 0.73 | TP53 (0.42) | ALDH1A1TSHRCYP3A4TDP1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727443-B1 | Catalyst for olefin polymerization and process for producing olefin polymers | TOSOH CORP (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5807938-A | Catalyst for olefin polymerization and process for producing olefin polymers | TOSOH CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0727443-A1 | Catalyst for olefin polymerization and process for producing olefin polymers | Tosoh Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |