Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12715451 | 0.80 | CALM1 (0.42) | ESR1ESR2CALM1IDO1ABAT | |
| SCHEMBL9412745 | 0.79 | ALDH1A1 (0.41) | IDO1CA2TAAR1ALDH1A1CYP2C19 | |
| SCHEMBL17937819 | 0.77 | IDO1 (0.41) | IDO1SLC6A2TAAR1ALDH1A1SLC6A4 | |
| SCHEMBL27999991 | 0.77 | IDO1 (0.52) | CALM1IDO1CA2TAAR1SIGMAR1 | |
| SCHEMBL17937673 | 0.77 | IDO1 (0.41) | IDO1TAAR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL49102 | 0.76 | TP53 (0.42) | CALM1IDO1KDM4EALDH1A1TP53 | |
| SCHEMBL7748341 | 0.74 | ALDH1A1 (0.52) | CALM1KDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL28682010 | 0.73 | ESR1 (0.50) | ESR1ESR2IDO1ABATCA2 | |
| SCHEMBL734092 | 0.72 | ALDH1A1 (0.44) | CA2ALDH1A1TP53CYP3A4 | |
| SCHEMBL15948125 | 0.71 | ESR1 (0.48) | ESR1ESR2IDO1ABATCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259094-A1 | Method of attachment of a biomolecule to a solid surface | GE HEALTHCARE UK LIMITED (GB) | 2004-12-23 | — | — | US | claimed |
| EP-1459067-A2 | METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE | Amersham Biosciences UK Limited (GB) | 2004-09-22 | — | — | EP | claimed |
| WO-2003027677-A2 | METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2003-04-03 | — | — | WO | claimed |
| US-20040259094-A1 | Method of attachment of a biomolecule to a solid surface | GE HEALTHCARE UK LIMITED (GB) | 2004-12-23 | — | — | US | disclosed |
| EP-1459067-A2 | METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE | Amersham Biosciences UK Limited (GB) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003027677-A2 | METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2003-04-03 | — | — | WO | disclosed |