SCHEMBL963476

SCHEMBL963476

CO[SiH](Cc1ccc(CCl)cc1)OC

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
TTR P02766 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17937819 0.82 IDO1 (0.41)
SCHEMBL9412745 0.79 ALDH1A1 (0.41) CA2
SCHEMBL384789 0.79 AGXT (0.43) CA1CA2
SCHEMBL6890461 0.77 ESR1 (0.44) CA2
SCHEMBL483523 0.77 TDP1 (0.44)
SCHEMBL17937673 0.77 IDO1 (0.41)
SCHEMBL49102 0.76 TP53 (0.42)
SCHEMBL9505652 0.74 TP53 (0.40) CA1CA2
SCHEMBL7748341 0.74 ALDH1A1 (0.52)
SCHEMBL28742900 0.73 CA1 (0.34) CA1CA2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118562039-A Preparation method of 3D bicontinuous hydrophilic polystyrene monolithic column 中国石油大学(华东) 2024-08-30 CN claimed
CN-118562039-A Preparation method of 3D bicontinuous hydrophilic polystyrene monolithic column 中国石油大学(华东) 2024-08-30 CN disclosed
US-20110000658-A1 HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2011-01-06 US disclosed
EP-2239137-A1 HYDROPHILIC MEMBERS FUJIFILM Corporation (JP) 2010-10-13 EP disclosed