Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 12/20 | 0.60 |
| ▸ | MMP2 | P08253 | 10/20 | 0.60 |
| ▸ | MMP1 | P03956 | 9/20 | 0.60 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744256 | 0.82 | MMP13 (0.55) | MMP13MMP1MMP8ALDH1A1CA12 | |
| SCHEMBL7748901 | 0.81 | MMP13 (0.61) | MMP13MMP2MMP1MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL7751277 | 0.78 | MMP13 (0.62) | MMP13MMP2MMP1SOS1MMP3 | |
| SCHEMBL7210638 | 0.76 | MMP13 (0.50) | MMP13MMP2MMP1SOS1MMP3 | |
| SCHEMBL8189068 | 0.76 | MMP1 (0.69) | MMP13MMP2MMP1SOS1MMP3 | |
| SCHEMBL6769491 | 0.75 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6767563 | 0.75 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6767568 | 0.75 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6764638 | 0.74 | MMP13 (0.67) | MMP13MMP2MMP1MMP14 | |
| SCHEMBL7210834 | 0.72 | MMP13 (0.61) | MMP13MMP2MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984959-A4 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO CO (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-0984959-A1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998039326-A1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |