Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 11/20 | 0.61 |
| ▸ | MMP2 | P08253 | 4/20 | 0.61 |
| ▸ | MMP1 | P03956 | 2/20 | 0.61 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748825 | 0.81 | MMP13 (0.60) | MMP13MMP2MMP1MMP8MMP3 | |
| SCHEMBL6767482 | 0.75 | MMP13 (0.67) | MMP13MMP2MMP1MMP8MMP3 | |
| SCHEMBL7744256 | 0.74 | MMP13 (0.55) | MMP13MMP1MMP8ALDH1A1CA1 | |
| SCHEMBL7178204 | 0.73 | MMP13 (0.75) | MMP13MMP2MMP1MMP8MMP3 | |
| SCHEMBL7178201 | 0.73 | MMP13 (0.75) | MMP13MMP2MMP1MMP8MMP3 | |
| SCHEMBL7208410 | 0.70 | MMP13 (0.71) | MMP13MMP2MMP1MMP8MMP3 | |
| Diphenylsulfane SCHEMBL27619579 | 0.70 | SIRT1 (0.59) | ALDH1A1HPGDSIRT1 | |
| Diphenylsulfane SCHEMBL28278324 | 0.70 | SIRT1 (0.59) | ALDH1A1HPGDSIRT1 | |
| SCHEMBL7813482 | 0.70 | MMP2 (0.61) | MMP13MMP2MMP1MMP8MMP3 | |
| SCHEMBL11653890 | 0.69 | HSD11B1 (0.46) | MMP13MMP2MMP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984959-A4 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO CO (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-0984959-A1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998039326-A1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |