Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336567 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDTDP1SMN1; SMN2MEN1 | |
| SCHEMBL2572335 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10706756 | 0.77 | ADRB2 (0.65) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL6266863 | 0.76 | RARB (0.63) | KDM4ERXRARXRBRXRG | |
| SCHEMBL3977527 | 0.76 | RARB (0.63) | KDM4ERXRARXRBRXRG | |
| SCHEMBL8769909 | 0.76 | RARB (0.63) | KDM4ERXRARXRBRXRG | |
| SCHEMBL7331535 | 0.76 | RARB (0.63) | KDM4ERXRARXRBRXRG | |
| SCHEMBL10871804 | 0.76 | RARB (0.63) | KDM4ERXRARXRBRXRG | |
| SCHEMBL8986580 | 0.76 | RARB (0.63) | KDM4ERXRARXRBRXRG | |
| SCHEMBL9799861 | 0.76 | RARB (0.63) | KDM4ERXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |