Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22520945 | 0.81 | CES2 (0.48) | KDM4EALDH1A1GAAACHEGLA | |
| SCHEMBL14454097 | 0.81 | POLB (0.43) | KDM4EPOLBATMALDH1A1HSD17B10 | |
| SCHEMBL9512487 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10CFTRGAA | |
| SCHEMBL7748934 | 0.79 | ALDH1A1 (0.46) | KDM4EPOLBALDH1A1GAAGLA | |
| SCHEMBL1613338 | 0.79 | MMP2 (0.43) | KDM4EPOLBALDH1A1HSD17B10CFTR | |
| SCHEMBL11532613 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10CFTRGLA | |
| SCHEMBL11446092 | 0.75 | GPR35 (0.51) | KDM4EPOLBALDH1A1HSD17B10GAA | |
| SCHEMBL14454101 | 0.75 | MEN1 (0.44) | KDM4EPOLBALDH1A1GAAMAPK1 | |
| SCHEMBL689849 | 0.74 | CD44 (0.48) | KDM4EPOLBALDH1A1HSD17B10IKBKB | |
| SCHEMBL8061202 | 0.73 | KDM4E (0.47) | KDM4EPOLBATMALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382216-B1 | Novel substituted acetamide compounds | TOYO BOSEKI (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5041462-A | Novel substituted acetamide compounds and use as anti-allergic agents | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0382216-A1 | Novel substituted acetamide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4191840-A | Oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-03-04 | — | — | US | disclosed |