Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323712 | 0.82 | CA1 (0.47) | TSHRSMN1; SMN2CA1FDPS | |
| SCHEMBL3332157 | 0.77 | TSHR (0.41) | TSHRSMN1; SMN2CHRM1AKR1A1CHRM3 | |
| SCHEMBL11683234 | 0.76 | TDP1 (0.42) | TSHRSMN1; SMN2CHRM1AKR1A1CHRM3 | |
| SCHEMBL8012001 | 0.75 | TSHR (0.40) | TSHRSMN1; SMN2CHRM1AKR1A1CHRM3 | |
| SCHEMBL17759040 | 0.73 | LMNA (0.43) | TSHRSMN1; SMN2CHRM1AKR1A1CHRM3 | |
| SCHEMBL10027320 | 0.72 | TSHR (0.37) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL13538556 | 0.72 | CHRM1 (0.36) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27305175 | 0.72 | GABRP (0.38) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL514688 | 0.72 | — | — | |
| SCHEMBL18271802 | 0.72 | TSHR (0.38) | TSHRSMN1; SMN2CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001044145-A1 | METHOD FOR THE MANUFACTURE OF OLEFINS | FORTUM OIL AND GAS OY (FI) | 2001-06-21 | — | — | WO | disclosed |