Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917943 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAALOX12HPGDSMN1; SMN2 | |
| SCHEMBL15730295 | 0.76 | — | — | |
| SCHEMBL13967044 | 0.75 | NPSR1 (0.50) | ALDH1A1LMNAALOX12HPGDSMN1; SMN2 | |
| SCHEMBL4570753 | 0.74 | HPGD (0.48) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL4570748 | 0.72 | SMN1; SMN2 (0.49) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL215902 | 0.71 | KDM4E (0.37) | ALDH1A1LMNAALOX12MEN1KMT2A | |
| SCHEMBL10278754 | 0.71 | ALDH1A1 (0.45) | ALDH1A1LMNAALOX12HPGDSMN1; SMN2 | |
| SCHEMBL10278735 | 0.69 | GAA (0.36) | ALDH1A1LMNAALOX12HPGDSMN1; SMN2 | |
| SCHEMBL12410094 | 0.68 | ALDH1A1 (0.59) | ALDH1A1LMNAALOX12HPGDSMN1; SMN2 | |
| SCHEMBL21389407 | 0.68 | KMT2A (0.42) | ALDH1A1LMNAHPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053342-A2 | NUCLEIC ACID DELIVERY VEHICLES | Genzyme Corporation (US) | 2000-11-22 | — | — | EP | claimed |
| WO-1999040214-A2 | NUCLEIC ACID DELIVERY VEHICLES | GENZYME CORPORATION (US) | 1999-08-12 | — | — | WO | claimed |
| US-6287857-B1 | TRANSFECTING OR INFECTING LIVER CELLS; ADENO-ASSOCIATED VIRUS VECTOR BONDED TO POLYOXYETHYLENE GLYCOL LINKER AND CELL SURFACE MOLECULE COMPRISING FIBER KNOB PROTEIN, PULLULAN, HEPATOCYTE GROWTH FACTOR, GALACTOSE AND ASIALOFETUIN | GENZYME CORPORATION | 2001-09-11 | — | — | US | disclosed |
| WO-2001043779-A2 | ANTI-HIV-1 CONJUGATES FOR TREATMENT OF HIV DISEASE | TANOX, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| EP-1053342-A2 | NUCLEIC ACID DELIVERY VEHICLES | Genzyme Corporation (US) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040214-A2 | NUCLEIC ACID DELIVERY VEHICLES | GENZYME CORPORATION (US) | 1999-08-12 | — | — | WO | disclosed |