Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 6/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570748 | 0.83 | SMN1; SMN2 (0.49) | HPGDSMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL9999887 | 0.79 | PTGS1 (0.46) | HPGDHTTALDH1A1FAAHHDAC3 | |
| SCHEMBL24474075 | 0.78 | SMN1; SMN2 (0.64) | HPGDSMN1; SMN2HTTALDH1A1FAAH | |
| SCHEMBL28488205 | 0.78 | SMN1; SMN2 (0.64) | HPGDSMN1; SMN2HTTALDH1A1FAAH | |
| SCHEMBL19401301 | 0.77 | HPGD (0.56) | HPGDSMN1; SMN2HTTALDH1A1FAAH | |
| SCHEMBL12109385 | 0.77 | SMN1; SMN2 (0.63) | HPGDSMN1; SMN2HTTALDH1A1FAAH | |
| SCHEMBL18825259 | 0.77 | FAAH (0.40) | HPGDSMN1; SMN2HTTALDH1A1FAAH | |
| SCHEMBL27397700 | 0.74 | CASP2 (0.57) | HPGDSMN1; SMN2HTTALDH1A1FAAH | |
| SCHEMBL23226018 | 0.74 | CASP2 (0.57) | HPGDSMN1; SMN2HTTALDH1A1FAAH | |
| SCHEMBL7749425 | 0.74 | ALDH1A1 (0.38) | HPGDSMN1; SMN2HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120164635-A1 | LARGE STOKE SHIFT NIR DYES | VANDERBILT UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
| US-8168804-B2 | Large stoke shift NIR dyes | VANDERBILT UNIVERSITY (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090029405-A1 | LARGE STOKE SHIFT NIR DYES | VANDERBILT UNIVERSITY | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164635-A1 | LARGE STOKE SHIFT NIR DYES | SLC7A5, SLC43A1, SPIN3 | HPGD 3230/4885SMN1; SMN2 1050/4885HTT 3647/4885 |
| US-20090029405-A1 | LARGE STOKE SHIFT NIR DYES | SLC7A5, SLC43A1, SPIN3 | HPGD 3230/4885SMN1; SMN2 1050/4885HTT 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.