Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570753 | 0.83 | HPGD (0.48) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL9999885 | 0.81 | PTGS1 (0.37) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL4570745 | 0.79 | HTT (0.69) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL22422905 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL7749425 | 0.72 | ALDH1A1 (0.38) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL13967044 | 0.71 | NPSR1 (0.50) | SMN1; SMN2HPGDHTTALDH1A1TSHR | |
| SCHEMBL12290101 | 0.71 | CYP3A4 (0.49) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL25734966 | 0.71 | HTT (0.73) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL12109385 | 0.71 | SMN1; SMN2 (0.63) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL27317502 | 0.70 | TSHR (0.47) | ALDH1A1MAPTTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120164635-A1 | LARGE STOKE SHIFT NIR DYES | VANDERBILT UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
| US-8168804-B2 | Large stoke shift NIR dyes | VANDERBILT UNIVERSITY (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090029405-A1 | LARGE STOKE SHIFT NIR DYES | VANDERBILT UNIVERSITY | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164635-A1 | LARGE STOKE SHIFT NIR DYES | SLC7A5, SLC43A1, SPIN3 | SMN1; SMN2 1050/4885HPGD 3230/4885HTT 3647/4885 |
| US-20090029405-A1 | LARGE STOKE SHIFT NIR DYES | SLC7A5, SLC43A1, SPIN3 | SMN1; SMN2 1050/4885HPGD 3230/4885HTT 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.