Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749482 | 1.00 | VCAM1 (0.42) | VCAM1GPR35CYP1A2TSHRMAPK1 | |
| SCHEMBL7749617 | 0.88 | VCAM1 (0.45) | VCAM1GPR35CYP1A2TSHRMAPK1 | |
| SCHEMBL7749628 | 0.88 | VCAM1 (0.45) | VCAM1GPR35CYP1A2TSHRMAPK1 | |
| SCHEMBL7744960 | 0.87 | VCAM1 (0.38) | VCAM1GPR35CYP1A2TSHRMAPK1 | |
| SCHEMBL7744957 | 0.87 | VCAM1 (0.38) | VCAM1GPR35CYP1A2TSHRMAPK1 | |
| SCHEMBL3354328 | 0.83 | LMNA (0.44) | CYP1A2TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL23577629 | 0.81 | MEN1 (0.45) | VCAM1CYP1A2MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL6354483 | 0.81 | SLC9A1 (0.45) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL6354489 | 0.81 | SLC9A1 (0.45) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL7745002 | 0.80 | ATM (0.39) | VCAM1GPR35CYP1A2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781757-B1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LAB (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0610384-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LAB (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0781757-A1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5637765-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-06-10 | — | — | US | disclosed |
| US-5633399-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-05-27 | — | — | US | disclosed |
| US-5576455-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1996-11-19 | — | — | US | disclosed |