Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744960 | 1.00 | VCAM1 (0.38) | VCAM1SLC6A4GRIA2GPR35CYP1A2 | |
| SCHEMBL7744997 | 0.88 | ATM (0.39) | VCAM1GRIA2GPR35CYP1A2TSHR | |
| SCHEMBL7745002 | 0.88 | ATM (0.39) | VCAM1GRIA2GPR35CYP1A2TSHR | |
| SCHEMBL7749482 | 0.87 | VCAM1 (0.42) | VCAM1GRIA2GPR35CYP1A2PDK1 | |
| SCHEMBL7749490 | 0.87 | VCAM1 (0.42) | VCAM1GRIA2GPR35CYP1A2PDK1 | |
| SCHEMBL9052145 | 0.82 | GPR35 (0.39) | VCAM1SLC6A4GPR35PDK1TSHR | |
| SCHEMBL27837949 | 0.81 | TSHR (0.41) | GPR35CYP1A2PDK1TSHRMAPK1 | |
| SCHEMBL7750957 | 0.80 | ALDH1A1 (0.42) | VCAM1SLC6A4CYP1A2MAPK1TDP1 | |
| SCHEMBL7749617 | 0.79 | VCAM1 (0.45) | VCAM1GRIA2GPR35CYP1A2TSHR | |
| SCHEMBL2729263 | 0.79 | ATM (0.42) | VCAM1CYP1A2TSHRATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781757-B1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LAB (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0610384-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LAB (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0781757-A1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5637765-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-06-10 | — | — | US | disclosed |
| US-5633399-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-05-27 | — | — | US | disclosed |
| US-5576455-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1996-11-19 | — | — | US | disclosed |