Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.59 |
| ▸ | MMP9 | P14780 | 5/20 | 0.59 |
| ▸ | MMP13 | P45452 | 5/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP3 | P08254 | 2/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787429 | 0.90 | MMP1 (0.50) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL6785767 | 0.84 | KCNA3 (0.49) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL6795694 | 0.84 | MMP1 (0.59) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL6796783 | 0.81 | MMP1 (0.43) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL6789202 | 0.74 | MMP13 (1.00) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL6789714 | 0.73 | MMP1 (0.50) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL6785881 | 0.72 | MMP13 (0.49) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7360886 | 0.69 | ADAM17 (0.61) | MMP1MMP9MMP13MMP2ADAM17 | |
| SCHEMBL7749955 | 0.69 | MMP1 (0.46) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL10900845 | 0.69 | HTR1A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983257-A4 | AROMATIC SULFONYL ALPHA-CYCLOAMINO HYDROXAMIC ACID COMPOUNDS | MONSANTO CO (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-0983257-A1 | AROMATIC SULFONYL ALPHA-CYCLOAMINO HYDROXAMIC ACID COMPOUNDS | Monsanto Company (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998039315-A1 | AROMATIC SULFONYL ALPHA-CYCLOAMINO HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |