Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282787 | 0.87 | KDM4E (0.58) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL476926 | 0.87 | KDM4E (0.58) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL20294662 | 0.86 | ALDH1A1 (0.57) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL6259464 | 0.86 | ALDH1A1 (0.57) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL20294664 | 0.86 | ALDH1A1 (0.57) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL6259576 | 0.84 | ALDH1A1 (0.54) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL845556 | 0.84 | ALDH1A1 (0.77) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL3499274 | 0.84 | ALDH1A1 (0.77) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL6261469 | 0.83 | ALDH1A1 (0.53) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL6262312 | 0.82 | ALDH1A1 (0.52) | ALDH1A1POLBKDM4ETP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010041716-A1 | Compositions and methods for locally treating inflammatory diseases | REGENTS OF THE UNIVESITY OF MICHIGAN, THE | 2001-11-15 | — | — | US | disclosed |
| WO-2001041755-A2 | TOPICAL COMPOSITIONS COMPRISING THALIDOMIDE FOR THE TREATMENT OF INFLAMMATORY DISEASES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041716-A1 | Compositions and methods for locally treating inflammatory diseases | TNF, TSLP, LITAF | ALDH1A1 1421/4885POLB 1633/4885KDM4E 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.