SCHEMBL26909710

SCHEMBL26909710

CCSc1ccc(C)c(N)c1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
AOC3 Q16853 1/20 0.34
CD44 P16070 1/20 0.33
LMNA P02545 3/20 0.31
MAPT P10636 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HSP90AA1 P07900 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
CYP3A4 P08684 1/20 0.31
NPC1 O15118 1/20 0.31
NFKB1 P19838 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6734336 0.81 CD44 (0.46) POLBAOC3CD44MAPTKDM4E
SCHEMBL7750244 0.77 NPC1 (0.37) POLBAOC3LMNAMAPTALDH1A1
SCHEMBL646183 0.75 POLB (0.42) POLBCD44LMNAMAPTALDH1A1
SCHEMBL9131932 0.74 AOC3 (0.32) AOC3
SCHEMBL8763695 0.72 AOC3 (0.33) AOC3MAPTALDH1A1NPC1MEN1
SCHEMBL16676184 0.72 ALDH1A1 (0.48) AOC3LMNAMAPTALDH1A1KDM4E
SCHEMBL9578929 0.72 ESR1 (0.37) POLBCD44LMNAMAPTALDH1A1
SCHEMBL409314 0.72 POLB (0.61) POLBCD44LMNAMAPTALDH1A1
SCHEMBL24439951 0.69 POLB (0.34) POLBCD44MAPTALDH1A1NOS3
SCHEMBL8764598 0.69 NPC1 (0.32) AOC3NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12544958-B2 Method of making low specific gravity polishing pads ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2026-02-10 US disclosed
US-12528152-B2 CMP pad having ultra expanded polymer microspheres ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2026-01-20 US disclosed
US-12447581-B2 Chemical mechanical planarization pad having polishing layer with multi-lobed embedded features ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2025-10-21 US disclosed
US-20240009798-A1 Chemical Mechanical Planarization Pad Having Polishing Layer with Multi-lobed Embedded Features U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-01-11 US disclosed
US-20230390889-A1 CMP PAD HAVING POLISHING LAYER OF LOW SPECIFIC GRAVITY U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-12-07 US disclosed
US-20230390888-A1 CMP PAD HAVING ULTRA EXPANDED POLYMER MICROSPHERES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-12-07 US disclosed
US-20230390970-A1 METHOD OF MAKING LOW SPECIFIC GRAVITY POLISHING PADS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528152-B2 CMP pad having ultra expanded polymer microspheres SRM, SMS, PAM POLB 108/4885AOC3 287/4885CD44 449/4885
US-12544958-B2 Method of making low specific gravity polishing pads SRM, HMGB1, ACP1 POLB 137/4885AOC3 638/4885CD44 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.