Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | TSPO | P30536 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499739 | 0.89 | MAOB (0.48) | MAOBTSPOSRD5A2KDM4EALDH1A1 | |
| SCHEMBL7499481 | 0.86 | MAOB (0.53) | MAOBTSPOSRD5A2KDM4EALDH1A1 | |
| SCHEMBL7750388 | 0.83 | TSPO (0.56) | TSPOKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL7750398 | 0.82 | TSPO (0.69) | TSPO | |
| SCHEMBL7750505 | 0.81 | TSPO (0.61) | TSPOKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL5702540 | 0.76 | TSPO (0.81) | TSPOMAPTTP53 | |
| SCHEMBL8959235 | 0.74 | TSPO (0.71) | TSPOKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL7497799 | 0.74 | TSPO (0.71) | TSPOKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL7751594 | 0.72 | TSPO (0.50) | TSPOKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL7493872 | 0.72 | TSPO (0.63) | TSPOMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262045-B1 | TREATMENT OF ANXIETY; SLEEP DISORDER; EPILEPSY; SPASTICITY; MUSCLE CONTRACTURE OR AN EXTRAPYRAMIDAL SYNDROM; INDUCING OR MAINTAINING ANAESTHESIA | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |