Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600372 | 0.89 | TSPO (0.78) | TSPOSMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL7750388 | 0.88 | TSPO (0.56) | TSPORXFP1TSHRHSD17B10KMT2A | |
| SCHEMBL5702540 | 0.87 | TSPO (0.81) | TSPOMAPTTP53 | |
| SCHEMBL7750398 | 0.87 | TSPO (0.69) | TSPO | |
| SCHEMBL7501779 | 0.86 | TSPO (0.55) | TSPORXFP1TSHRHSD17B10KMT2A | |
| SCHEMBL7751594 | 0.84 | TSPO (0.50) | TSPORXFP1TSHRHSD17B10KMT2A | |
| SCHEMBL7745876 | 0.81 | MAOB (0.54) | TSPORXFP1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7497799 | 0.77 | TSPO (0.71) | TSPOTSHRKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL22082635 | 0.77 | TSPO (0.80) | TSPOSMN1; SMN2MAPTPOLBTP53 | |
| SCHEMBL14101694 | 0.77 | NPSR1 (0.49) | TSPORXFP1TSHRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262045-B1 | TREATMENT OF ANXIETY; SLEEP DISORDER; EPILEPSY; SPASTICITY; MUSCLE CONTRACTURE OR AN EXTRAPYRAMIDAL SYNDROM; INDUCING OR MAINTAINING ANAESTHESIA | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |