Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498096 | 0.89 | TSPO (0.56) | TP53POLBTSPOMAPTKMT2A | |
| SCHEMBL7493872 | 0.82 | TSPO (0.63) | TP53TSPOMAPT | |
| SCHEMBL7631555 | 0.81 | TSPO (0.65) | TSPOMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL5702445 | 0.81 | TSPO (0.67) | TP53POLBTSPOMAPT | |
| SCHEMBL7750398 | 0.80 | TSPO (0.69) | TSPO | |
| SCHEMBL7496967 | 0.78 | TSPO (0.60) | TSPO | |
| SCHEMBL7003823 | 0.77 | TSPO (0.71) | TP53POLBTSPOMAPTKDM4E | |
| SCHEMBL7001447 | 0.77 | TSPO (0.62) | TP53POLBTSPOMAPTKDM4E | |
| SCHEMBL16135917 | 0.77 | KDM4E (0.63) | TP53POLBTSPOMAPTKMT2A | |
| SCHEMBL7626419 | 0.76 | TSPO (0.58) | TP53TSPOMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262045-B1 | TREATMENT OF ANXIETY; SLEEP DISORDER; EPILEPSY; SPASTICITY; MUSCLE CONTRACTURE OR AN EXTRAPYRAMIDAL SYNDROM; INDUCING OR MAINTAINING ANAESTHESIA | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |