Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743270 | 1.00 | PPARA (0.41) | PPARAPPARGCTSSCTSKATM | |
| SCHEMBL7747433 | 0.93 | CTSS (0.40) | PPARAPPARGCTSSCTSKATM | |
| SCHEMBL7747398 | 0.81 | CTSS (0.46) | PPARAPPARGCTSSCTSKATM | |
| SCHEMBL4179331 | 0.81 | CTSK (0.44) | PPARAPPARGCTSSCTSKATM | |
| SCHEMBL7748907 | 0.80 | PPARA (0.45) | PPARAPPARGCTSSCTSKATM | |
| SCHEMBL7747410 | 0.80 | PPARA (0.45) | PPARAPPARGCTSSCTSKATM | |
| SCHEMBL7750570 | 0.74 | CTSK (0.43) | PPARAPPARGCTSSCTSKATM | |
| SCHEMBL7743269 | 0.74 | CTSK (0.43) | PPARAPPARGCTSSCTSKATM | |
| SCHEMBL31477252 | 0.74 | CTSK (0.43) | CTSSCTSKATMCTSLALDH1A1 | |
| SCHEMBL7943806 | 0.74 | CTSS (0.49) | PPARAPPARGCTSSCTSKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776322-B1 | METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-11-07 | — | — | EP | disclosed |
| EP-1116718-A2 | Method for the preparation of taxol and its derivatives | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-07-18 | — | — | EP | disclosed |
| US-5767282-A | Method for the preparation of taxol and its derivatives | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-06-16 | — | — | US | disclosed |