Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995586 | 0.83 | CTSK (0.54) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL8910232 | 0.81 | CTSS (0.46) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL9404277 | 0.81 | CTSS (0.46) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL7747398 | 0.81 | CTSS (0.46) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL7748907 | 0.80 | PPARA (0.45) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL7747410 | 0.80 | PPARA (0.45) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL12126937 | 0.79 | MMP13 (0.45) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL9404273 | 0.78 | MTNR1A (0.64) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL30777023 | 0.78 | PPARA (0.46) | CTSSCTSKCTSLCTSBMMP13 | |
| SCHEMBL8910228 | 0.78 | MTNR1A (0.64) | CTSSCTSKCTSLCTSBMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001076694-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-10-18 | — | — | WO | disclosed |