SCHEMBL7754281

SCHEMBL7754281

CCOCCCCC(O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CETP P11597 1/20 0.33
USP2 O75604 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754285 1.00 CES2 (0.35) CES2CES1ALDH1A1CETPUSP2
SCHEMBL8203331 0.98 CES2 (0.38) CES2CES1ALDH1A1CETPUSP2
SCHEMBL8054036 0.98 CES2 (0.38) CES2CES1ALDH1A1CETPUSP2
SCHEMBL8082918 0.98 CES2 (0.38) CES2CES1ALDH1A1CETPUSP2
SCHEMBL8610321 0.98 CES2 (0.38) CES2CES1ALDH1A1CETPUSP2
SCHEMBL8610319 0.98 CES2 (0.38) CES2CES1ALDH1A1CETPUSP2
SCHEMBL7754277 0.94 ALDH1A1 (0.36) CES2CES1ALDH1A1CETPPKM
SCHEMBL7634968 0.94 ALDH1A1 (0.36) CES2CES1ALDH1A1CETPPKM
SCHEMBL7750647 0.86 USP2 (0.39) CES2CES1CETPUSP2PKM
SCHEMBL7754322 0.86 TSHR (0.43) CES2CES1USP2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737733-B1 Liquid crystal compound having ferrielectric phase and liquid crystal composition MITSUBISHI GAS CHEMICAL CO (JP) 2001-02-21 EP disclosed
US-5728864-A AROMATIC DIESTERS FOR INJECTION BETWEEN SUBSTRATES FOR LIQUID CRYSTAL DISPLAYS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-03-17 US disclosed
EP-0737733-A1 Liquid crystal compound having ferrielectric phase and liquid crystal composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1996-10-16 EP disclosed