SCHEMBL7751005

SCHEMBL7751005

C=CC(=O)NCc1cccc(S(=O)(=O)NC(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 4/20 0.46
FBP1 P09467 2/20 0.46
TGM2 P21980 1/20 0.43
NAMPT P43490 1/20 0.42
HTR2B P41595 1/20 0.41
EGFR P00533 1/20 0.41
BTK Q06187 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP3A4 P08684 1/20 0.41
ROCK1 Q13464 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397556 0.90 ALDH1A1 (0.45) CCR1KDM4EALDH1A1FBP1TGM2
SCHEMBL393894 0.86 FBP1 (0.49) CCR1ALDH1A1FBP1TGM2EGFR
SCHEMBL7754578 0.85 FBP1 (0.44) ALDH1A1FBP1TGM2EGFRBTK
SCHEMBL7754564 0.84 ALDH1A1 (0.56) KDM4EALDH1A1TGM2NAMPTNPSR1
SCHEMBL393849 0.84 ALDH1A1 (0.47) CCR1ALDH1A1FBP1TGM2NAMPT
SCHEMBL397300 0.82 SMN1; SMN2 (0.50) KDM4EALDH1A1FBP1TGM2NAMPT
SCHEMBL394316 0.81 FBP1 (0.45) ALDH1A1FBP1TGM2NAMPTCYP3A4
SCHEMBL396034 0.80 ALDH1A1 (0.49) KDM4EALDH1A1TGM2CYP3A4ROCK1
SCHEMBL396171 0.80 HTR6 (0.55) NAMPTEGFRBTKHDAC8HDAC6
SCHEMBL392741 0.80 ALDH1A1 (0.47) ALDH1A1FBP1NAMPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US claimed
EP-1077392-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-02-21 EP disclosed
EP-0330239-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-22 EP disclosed
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
EP-0330239-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1989-08-30 EP disclosed